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Endocrine Abstracts

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ea0034p287 | Pituitary | SFEBES2014

An evolution of clinical practice: the impact of changes in clinical management of non-functioning pituitary adenomas on long-term pituitary function and risk of recurrence

O'Reilly Michael , Pearce Harriet , Bugg Gabriella , Mitchell Rosalind , Toogood Andy , Gittoes Neil , Ayuk John

Management of newly-diagnosed non-functioning pituitary adenomas (NFPAs) has evolved over the last decade. Whilst surgical debulking remains the mainstay of treatment for patients presenting with compressive disease, the use of pituitary irradiation has declined, with greater emphasis on observation or further surgical debulking. We aimed to compare outcomes of treatment for NFPAs at our institution since 2004 with older management strategies.We reviewed...
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ea0037gp.20.05 | Pituitary – Hypopituitarism | ECE2015

Long-term follow-up of 520 patients with non-functioning pituitary adenomas from two large tertiary referral centres: a UK-Republic of Ireland collaborative study

O'Reilly Michael , Gupta Saket , Thompson C A , Pearce Harriet , Bugg Gabriella , Toogood Andrew , Gittoes Neil , Thompson Christopher , Ayuk John

AbstractNon-functioning pituitary adenomas (NFPAs) are the most common pituitary tumours, often presenting with chiasmal compression or hypopituitarism. Surgical resection, accompanied by radiotherapy (RTX) in selected cases, is the treatment of choice for compressive tumours. Long-term health consequences of NFPAs and their treatment are unclear. In this retrospective study, we aimed to assess long-term pituitary function, recurrence and mortality in a ...
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ea0038p312 | Pituitary | SFEBES2015

ACTH and gonadotrophin deficiency predict mortality in patients treated for non-functioning pituitary adenomas (NFPAs) in the UK and Republic of Ireland: long-term follow-up of 519 patients across two tertiary referral centres

O'Reilly Michael , Reulen Raoul , Gupta Saket , Dineen Rosemary , Thompson C , Pearce Harriet , Bugg Gabriella , Toogood Andrew , Gittoes Neil , Thompson Christopher , Ayuk John

Non-functioning pituitary adenomas (NFPAs) are the commonest subtype of pituitary tumour. Surgical resection, accompanied by radiotherapy (RTX) in selected cases, is the treatment of choice for compressive tumours. Long-term health consequences of treatment for NFPAs are unclear. In this retrospective study, we assessed long-term pituitary function and mortality rates in a large NFPA cohort across two tertiary centres in the UK and Ireland.Case-note revi...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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